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論文・著書

論文・総説・著書

under line: lab members

*corresponding author

学会発表

うち国際学会招待講演のみ

[2015]

Yamazaki, S., Yamamoto, K., *Harata, M "Contribution of nuclear actin to transcription regulation." Genomics Data 4, 127-129 (2015) doi:10.1016/j.gdata.2015.04.009 

 

Georgieva M, Staneva D, Uzunova K, Efremov T, Balashev K, Harata M, *Miloshev G. "The linker histone in Saccharomyces cerevisiae interacts with actin-related protein 4 and both regulate chromatin structure and cellular morphology." Int J Biochem Cell Biol. 59, 182-192 (2015) PMID:25542182, doi: 10.1016/j.biocel.2014.12.006

 

Yamazaki, S.Yamamoto, K., Tokunaga, M., Sakata-Sogawa, K., *Harata, M., "Nuclear actin activates human transcription factor genes including the OCT4 gene." Biosci Biotechnol Biochem. 79, 242-246 (2015) PMID: 25355676, doi: 10.1080/09168451.2014.972332 

 

[2014]

Osakabe, A., Takahashi, Y., Murakami, H., Otawa, K., Tachiwana, H., Oma, Y., Hitoshi Nishijima, H., Shibahara, K., *Kurumizaka, H., *Harata, M. "DNA binding properties of the actin-related protein Arp8 and its role in DNA repair.” PLOS One 9, e108354. (2014) PMID: 25299602, doi: 10.1371/journal.pone.0108354 

 

Horigome, C., Oma, Y., Konishi, T., Schmid, R., Marcomini, I., Hauer, M.H., Dion, V., Harata, M., and *Gasser, S.M. “SWR1 and INO80 chromatin remodelers contribute to DNA double-strand break perinuclear anchorage site choice.” Mol Cell 55, 626-639 (2014) PMID: 25066231, doi: 10.1016/j.molcel.2014.06.027  

 

Kalendova, A., Kalasova, I., Yamazaki, S., Ulicna, L., Harata, M., and *Hozak, P. “Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block.” Histochem Cell Biol 142, 139-152 (2014) PMID: 25002125, doi: 10.1007/s00418-014-1243-9 

 

Ui, A., Ogiwara, H., Nakajima, S., Kanno, S., Watanabe, R., Harata, M., Okayama, H., Harris, C.C., Yokota, J., Yasui, A., and *Kohno, T. “Possible involvement of LKB1-AMPK signaling in non-homologous end joining.” Oncogene 33, 1640-1648 (2014) PMID: 23584481, doi: 10.1038/onc.2013.125

 

Nishibuchi, I., Suzuki, H., Kinomura, A., Sun, J., Liu, N.A., Horikoshi, Y., Shima, H., Kusakabe, M., Harata, M., Fukagawa, T., and *Tashiro, K. “Reorganization of damaged chromatin by the exchange of histone variant H2A.Z-2.” Int J Radiat Oncol Biol Phys 89, 736-744 (2014) PMID: 24969791, doi: 10.1016/j.ijrobp.2014.03.031 

 

Konishi, T., and *Harata, M. “Improvement of the transformation efficiency of Sacchaaromyces cerevisiae by altering carbon sources in pre-culture.” Biosci Biotechnol Biochem 78, 1090-1093 (2014) PMID: 25036141, doi: 10.1080/09168451.2014.915730 

 

[2013]

Horikoshi, N., Sato, K., Shimada, K., Arimura, Y., Osakabe, A., Tachiwana, H., Hayashi-Takanaka, Y., Iwasaki, W., Kagawa, W., Harata, M., Kimura, H. and Kurumizaka, H.“Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2”Acta Crystallogr. D. (2013) 69, 12, 2431-2439

 

「核タンパク質と核骨格」原田昌彦

染色体と細胞核のダイナミクス(平岡泰、原口徳子編)化学同人 (2013) 

 

「翻訳の調節」原田昌彦

ベーシックマスター分子生物学(改訂版)(東中川徹、清水光弘、大山隆編)オーム社 (2013)

 

[2012]

Maruyama, E.O., Hor,i T., Tanabe, H., Kitamura, H., Matsuda, R., Tone, S., Hozak, P., Habermann, F.A., von Hase, J., Cremer, C., Fukagawa, T. and Harata, M. “The actin family memberArp6 and the histone variant H2A.Z are required for spatial positioning ofchromatin in chicken cell nuclei.” J. Cell Sci. 125, 3739-3743 (2012) 

 

高次エピゲノムと細胞骨格 [細胞工学, 31, 894-900] (2012)

北村大志・原田昌彦

 

The actin family member Arp6 and the histone variant H2A.Z are required for spatial positioning of chromatin in chicken cell nuclei. [ [Journal of Cell Science, 125、3739-3743(2012)] 

Ohfuchi Maruyama E, Hori T, Tanabe H, Kitamura H, Matsuda R, Tone S, Hozak P, Habermann FA, von Hase J, Cremer C, Fukagawa T, and Harata M

 

細胞核の構造とエピジェネティック制御 [化学と生物, 50, 4, 262-268] (2012)

尾間由佳子, 原田昌彦

 

[2011]

Actin-related proteins localized in the nucleus: From discovery to novel roles in nuclear organization.[Nucleus,2(1),(2011),38-46] 

Oma Y, Harata M*

 

農学生命科学を学ぶための入門生物学

豊水正昭、牧野周、原田昌彦、金山喜則、遠藤宣成、中嶋正道(編集)

東北大学出版会 (2011)

 

[2010]

ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.[PLoS One,5(10),(2010),e13554] Sun J, Oma Y, Harata M, Kono K, Shima H, Kinomura A, Ikura T, Suzuki H, Mizutani S, Kanaar R, Tashiro S.

 

Transcription-dependent rearrangements of actin and nuclear myosin I in the nucleolus.[Histochem Cell Biol,134(3),(2010),243-249] Philimonenko VV, Janacek J, Harata M, Hozak P.

 

Identification and characterization of two isoforms of the vertebrate H2A.Z histone variant.[Nucleic Acids Res.,38(13),(2010),4263-4273] Matsuda, R., Hori, T., Kitamura, H., Takeuchi, K., Fukagawa, T. and Harata, M*.

 

Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4.[Journal of Cell Science,123,(2010),1020-1030] Masahiro Kumeta, Shige H. Yoshimura, Masahiko Harata, and Kunio Takeyasu*

 

Actin-related protein Arp6 influences H2AZ-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores.[PLoS Genetics,6,(2010),e1000910] Yoshida, Y., Shimada, K., Oma, Y., Kalck, V., Akimura, K., Taddei, A., Iwahashi, H., Kugou, K., Ohta, K., Gasser, S.M. and Harata, M*.

 

[2009]

Involvement of actin-related protein Arp6 in organization of chromosomes.[Adv. Chromosome Sci., 3,(2009), 26-28] Ohfuchi Maruyama, E. and Harata, M*.

 

Cooperation of nuclear actin and myosin families: an approach with antibodies.[Adv. Chromosome Sci.,3,(2009), 169-170] Kitamura, H., Ohfuchi Maruyama, E., Matsuda, R. and Harata, M*.

 

The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair.[Exp Cell Res,315,(2009),206-217] Kitayama K, Kamo M, Oma Y, Matsuda R, Uchida T, Ikura T, Tashiro S, Ohyama T, Winsor B, Harata M*.

 

細胞核-遺伝情報制御と疾患 

平岡泰、原田昌彦、木村宏、田代聡 編集

実験医学増刊、羊土社 (2009)

 

[2008]

The nuclear actin-related protein Act3p/Arp4 influences yeast cell shape and bulk chromatin organization.[J Cell Biochem,104,(2008),59-67] Miloshev J, Harata M, Georgieva M*

 

Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks.[Current Biology,18,(2008),566-575] Shimada K, Oma Y, Schleker T, Kugou K, Ohta K, Harata M*, Gasser SM*

 

The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment.[Experimental Cell Research,314(4),(2008),859-868] Aoyama N, Oka A, Kitayama K, Kurumizaka H, Harata M*

 

「DNA複製と遺伝子発現」原田昌彦、大山隆

ベーシックマスター生化学 大山隆監修 オーム社 (2008)

 

分子細胞生物学辞典 

原田昌彦(分担執筆)

東京化学同人 (2008)

 

[2007]

The INO80 complex is required for damage-induced recombination.[Biochem Biophys Res Commun.,355,(2007),835-841] Kawashima S, Ogiwara H, Tada S, Harata M, Wintersberger U, Enomoto T, Seki M*

 

14. Actin-related protein Arp4 functions in kinetochore assembly.[Nucleic Acids Res.,35(9),(2007),3109-3117] Ogiwara H, Ui A, Kawashima S, Kugou K, Onoda F, Iwahashi H, Harata M, Ohta K, Enomoto T, Seki M.*

 

[2006]

Assembly of staphylococcal leukocidin into a pore-forming oligomer on detergent-resistant membrane microdomains, lipid rafts, in human polymorphonuclear leukocytes.[Biosci Biotechnol Biochem.,70,(2006),1300-1307] Nishiyama, A., Kaneko, J., Harata, M., and Kamio, Y.*

 

Vertebrate Arp6, a novel nuclear actin-related protein, interacts with heterochromatin protein 1.[Eur. J. Cell Biol.,85,(2006),411-421] Ohfuchi, E., Kato, M., Sasaki, M., Sugimoto, K., Oma, Y., and Harata, M*

 

Nuclear Dynamics: Approaches from Biochemistry, Molecular Cell Biology, and Visual Biology, eds. Nagata, S. and Takeyasu, K.

“Actin-related proteins involved in nuclear and chromatin dynamics” Harata, M.

Springer-Verlag Tokyo, Inc., Tokyo (2006)

 

DNA structure, chromatin, and gene expression, eds. Shimizu M and Kiyama R. “Nulcear actin-related proteins involved in the organization of euchromatin and heterochromatin” Harata M., Ohfuchi E., Oma Y

Transworld Research Network Inc. (2006)

 

[2005]

The nuclear actin-related protein Act3p/Arp4p is involved in the dynamics of chromatin modulating complexes.[Yeast,22,(2005),753-768] Sunada R, Goerzer I, Oma Y, Yoshida T, Suka N, Wintersberger U, Harata M*

 

細胞核の分子生物学 水野重樹(編)

「クロマチンレベルの転写制御機構」原田昌彦

朝倉書店 (2005)

 

[2004]

18. Fission yeast Arp6 is required for telomere silencing but functions independently of Swi6.[Nucleic Acids Res.,32,(2004),736-741] Ueno M*, Murase T, Kibe T, Ohashi N, Tomita K, Murakami Y, Uritani M, Ushimaru T, Harata M

 

 Molecular cloning and expression analysis of vitellogenin in scallop, Patinopecten yessoensis (Bivalvia, Mollusca).[Mol. Reprod. Dev.,67,(2004),273-281] Osada, M., Harata., M., Kishida, M., Kijima, A.

 

[2003]

The brain-specific actin-related protein ArpNα interacts with the transcriptional co-repressor CtBP.[Biochem. Biophys. Res. Commun.,301,(2003),521-528] Oma Y,Nishimori K,Harata M

 

「核内アクチンファミリーの分子機能」原田昌彦、尾間由佳子

細胞核のダイナミクス 竹安邦夫、米田悦啓(編)

シュプリンガー・フェアラーク東京 pp177-186 (2004) 

 

[2002]

Brain-specific expression of the nuclear actin-related protein ArpNα and its involvement in mammalian SWI/SNF chromatin remodeling complex.[Biochem. Biophys. Res. Commun.,299,(2002),328-334] Kuroda Y, Oma Y, Nishimori K, Ohta T, Harata M

 

Alternative splicing products of the gene for a human nuclear actin-related protein, hArpNβ/Baf53, encode a protein isoform, hArpNβS, localized in the cytoplasm.[Biosci. Biotechnol. Biochem.,66,(2002),1740-1743] Ohfuchi E, Nishimori K, Harata M

 

Correlation between chromatin association and transcriptional regulation for the Act3p/Arp4 nuclear actin-related protein of Saccharomyces cerevisiae.[Nucleic Acids Res,30,(2002),1743-1750] Harata M*, Zhang Y, Stillman DJ, Matsui D, Oma Y, Nishimori K, and Mochizuki R

 

Vertebrate Sex Chromosomes, eds. N. Takagi “Z and W chromosomes of chickens: studies on their gene functions in sex determination and sex differentiation.” S. Mizuno, R. Kunita, O. Nakabayashi , Y Kuroda, N. Arai, M. Harata, A. Ogawa, Y Itoh, M. Teranishi and T. Hori, Kager (2002)

 

[2001]

Identification of two cDNAs for human actin-related proteins (Arps) that have remarkable similarity to conventional actin.[Biochim. Biophys. Acta,1522,(2001),130-133] Harata M, Nishimori K, Hatta S

 

Novel actin-related proteins in vertebrates : similarities of structure and expression pattern to Arp6 localized on Drosophila heterochromatin.[Gene,268,(2001),133-140]  

 

The N-terminal internal region of BLM is required for the formation of dots/rod-like structures which are associated with SUMO-1.[Biochem. Biophys. Res. Commun.,286, (2001), 322-327]  

 

Absence of Z-chromosome inactivation for five genes in male chickens.[Chromosome Res.,9, (2001), 457-468]  

 

A nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, is involved in transcriptional regulation.[Yeast,18,(2001),S77] Oma. Y, Mochizuki, R., Wintersberger, U., and Harata, M.

 

 A nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, is involved in transcriptional regulation.[Yeast,18,(2001),S77] Oma, Y., Mochizuki, R., Wintersbeger, U., Harata, M.

 

Co-localization of chicken DNA topoisomeraseIIα, but not β, with sites of DNA replication and possible involvement of a C-terminal region of α throught its binding to PCNA.[Chromosoma(Berl),110,(2001),102-114] Niimi,A., Suka,N., Harata, M., Kikuchi, A., and Mizuno, S.

 

[2000]

Actin-related proteins in the nucleus and their involvement in the function of chromatio(Review).[Tohoku J. Agri. Res,51,(2000),29-38] Harata, M., Oma, Y., Mochizuki, R., Mizuno, S.

 

Multiple actin-related proteins of Saccharomyces cerevisiae are present in the nucleus.[J. Biochem,128,(2000),665-671] Harata, M., Oma, Y., Tabuchi, T., Zhang, Y., Stillman, D. J., and Mizuno S

 

[1999]

Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues.[Bioscience, Biotechnology and Biochemistry,63(5),(1999),917-923] Harata, M., Mochizuki, R., and Mizuno, S.

 

The nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, interacts with core histones.[Molecular Biology of the Cell,10,(1999),2595-2605] Harata, M*., Oma, Y., Mizuno, S., Jiang, Y. W., Stillman, D. J., and Wintersberger, U.

 

[1997]

Purification and nucleic-acid binding properties of Saccharomyces cerevisiae protein involved in the control of ploidy.[European Journal of Biochemistry,249,(1997),309-317]  

 

A nuclear matrix-associated high molecular weight nuclear anitigen, HMNA, of chicken and marked decrease of its immunoreactivity during the progression of S-phase.[Jouranl of Cell Science,110,(1997),3031-3041] Shimada, K., Harata, M. and Mizuno, S.

 

[1995]

The actin-related protein Act3p of Saccharomyces cerevisiae is located in the nucleus.[Mol. Biol. Cell.,6,(1995),1263-1270] Weber, V., Harata, M., Hauser, H and Wintersberger, U.

 

[1994]

A new essential gene of Saccharomyces cerevisiae coding for an actin-relared protein.[Proc. Natl. Acad. Sci. U.S.A.,91,(1994),8258-8262] Harata, M., Karwan, A. and Wintersberger, U*.

 

[1993]

W-heterochromatin of chicken ; its unusual DNA components, late replication, and chromatin structure.[Genetica,88,(1993),93-105] Suka, N., Shinihara, Y., Saitoh, H., Ohtomo, K., Harata, M., Shpigelman, E. and Mizuno, S.

 

[1991]

クロマチンレベルの情報発現解析.[遺伝子工学実験Strategy & Practice,第17章,(1991),186-198] 原田昌彦、水野重樹

 

[1989]

Presence of female-specific bent-repetitive DNA sequences in the genomes of turkey and pheasant and their interactions with W-protein of chicken.[Chromosoma(Berl. ),98,(1989),250-258] Saitoh, H., Harata, M., Mizuno, S.

 

[1988]

Purification and characterization of W-protein : A DNA binding protein showing high affinity for the W chromosome-specific repetitive DNA sequences of chicken.[J. Biol. Chem.,263,(1988),13952-13961] Harata, M., Ohuchi, K., Ohhata, S., Kikuchi, A and Mizuno, S.

平成27年5月

Harata, M. "Contribution of nuclear actin and Arps to functional organization of the nucleus and chromatin", Institute for Protein Research (IRP) Seminar "Nuclear organization and actin-dependent mechanisms in genome stability", Osaka, Japan

 

平成26年12月

Harata, M. “Nuclear actin and ARPs involved in the functional organization of chromatin.”, The 2014 SCBB/IFCB Meeting, Philadelphia, USA、December 6)

 

平成25年8月

23rd Wilhelm Bernhard Workshop on the cell nucleus (Debrecen, Hungary)

Harata, M.

“Actin family proteins involved in the functional organization of the nucleus”

 

平成23年9月

Wenner-Gren Foundations International Symposium “Actin and actin-associated proteins from gene to polysomes” (Stockholm, Sweden)

Yoshida, T., Oma, Y., Kitamura, H., Shimada, K., Hozak, P., Gasser, S., Harata, M.

“Roles of actin-related proteins in chromatin function and nuclear organization”

 

平成25年8月

23rd Wilhelm Bernhard Workshop on the cell nucleus (Debrecen, Hungary)

Harata, M.

“Actin family proteins involved in the functional organization of the nucleus”

 

平成22年8月

52nd Symposium of the Society for Histochemistry (Prague, Czech Republic)

Harata, M.

“Roles of actin-related proteins in nuclear organization and genome function”

 

平成21年5月 

Chromosome Dynamics and Genome Stability (Villars, Switzerland)

Yoshida T, Shimada K, Oma Y, Kugou K, Ohta K, Hori T, Fukagawa T, Gasser S, Harata M.

“Actin-related proteins functional organization of chromatin”